2024

Akatsu C, Naito-Matsui Y, Abdu-Allah HHM, Imamura A, Long W, Ishida H, Takematsu H, Tsubata T.
Neu5Gc-mediated high-affinity interaction is dispensable for CD22 cis-ligands to regulate B cell signaling.
J Biol Chem. 2024 Sep;300(9):107630.

2023

Suganuma Y, Imamura A, Ando H, Kiso M, Takematsu H, Tsubata T, Ishida H.
Improved synthesis of CD22-binding sialosides and its application for further development of potent CD22 inhibitors.
Glycoconj J. 2023 Apr;40(2):225-246.

Takada M, Fukuhara D, Takiura T, Nishibori Y, Kotani M, Kiuchi Z, Kudo A, Beltcheva O, Ito-Nitta N, Nitta KR, Kimura T, Suehiro JI, Katada T, Takematsu H, Yan K.
Involvement of GLCCI1 in mouse spermatogenesis.
FASEB J. 2023 Jan;37(1):e22680.

2022

Hada I, Shimizu A, Takematsu H, Nishibori Y, Kimura T, Fukutomi T, Kudo A, Ito-Nitta N, Kiuchi Z, Patrakka J, Mikami N, Leclerc S, Akimoto Y, Hirayama Y, Mori S, Takano T, Yan K.
A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2.
J Am Soc Nephrol. 2022 Nov;33(11):2008-2025.

Doi H, Matsui T, Dijkstra JM, Ogasawara A, Higashimoto Y, Imamura S, Ohye T, Takematsu H, Katsuda I, Akiyama H.
Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production.
F1000Res. 2021 Jul 6;10:542.

Takahashi S, Fukuhara D, Kimura T, Fukutomi T, Tanaka E, Mikami N, Hada I, Takematsu H, Nishibori Y, Akimoto Y, Kiyonari H, Abe T, Huber O, Yan K.
USP40 deubiquitinates HINT1 and stabilizes p53 in podocyte damage.
Biochem Biophys Res Commun. 2022 Jul 23;614:198-206.

Enterina JR, Sarkar S, Streith L, Jung J, Arlian BM, Meyer SJ, Takematsu H, Xiao C, Baldwin TA, Nitschke L, Shlomchick MJ, Paulson JC, Macauley MS.
Coordinated changes in glycosylation regulate the germinal center through CD22.
Cell Rep. 2022 Mar 15;38(11):110512.

Akatsu C, Alborzian Deh Sheikh A, Matsubara N, Takematsu H, Schweizer A, Abdu-Allah HHM, Tedder TF, Nitschke L, Ishida H, Tsubata T.
The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45-/- immunodeficient B cells.
Sci Signal. 2022 Mar;15(723):eabf9570.

2021

Yang S, Gigout S, Molinaro A, Naito-Matsui Y, Hilton S, Foscarin S, Nieuwenhuis B, Tan CL, Verhaagen J, Pizzorusso T, Saksida LM, Bussey TM, Kitagawa H, Kwok JCF, Fawcett JW.
Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing.
Mol Psychiatry. 2021 Oct;26(10):5658-5668.

Alborzian Deh Sheikh A, Akatsu C, Abdu-Allah HHM, Suganuma Y, Imamura A, Ando H, Takematsu H, Ishida H, Tsubata T.
The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells.
J Immunol. 2021 Jun 1;206(11):2544-2551. Selected as one of "Top Reads".

Spruit CM, Nemanichvili N, Okamatsu M, Takematsu H, Boons GJ, de Vries RP.
N-Glycolylneuraminic Acid in Animal Models for Human Influenza A Virus.
Viruses. 2021 May 1;13(5):815.

Alborzian Deh Sheikh A, Gomaa S, Li X, Routledge M, Saigoh K, Numoto N, Angata T, Hitomi Y, Takematsu H, Tsuiji M, Ito N, Kusunoki S, Tsubata T.
A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides.
J Autoimmun. 2021 Jan;116:102571.

2020

Morise J, Yamamoto S, Midorikawa R, Takamiya K, Nonaka M, Takematsu H, Oka S.
Distinct Cell Surface Expression Patterns of N-Glycosylation Site Mutants of AMPA-Type Glutamate Receptor under the Homo-Oligomeric Expression Conditions.
Int J Mol Sci. 2020 Jul 19;21(14):5101

2019

Morise J, Suzuki KGN, Kitagawa A, Wakazono Y, Takamiya K, Tsunoyama TA, Nemoto YL, Takematsu H, Kusumi A, Oka S.
AMPA receptors in the synapse turnover by monomer diffusion.
Nat Commun. 2019 Nov 20;10(1):5245.

Kiuchi Z, Nishibori Y, Kutsuna S, Kotani M, Hada I, Kimura T, Fukutomi T, Fukuhara D, Ito-Nitta N, Kudo A, Takata T, Ishigaki Y, Tomosugi N, Tanaka H, Matsushima S, Ogasawara S, Hirayama Y, Takematsu H, Yan K.
GLCCI1 is a novel protector against glucocorticoid-induced apoptosis in T cells.
FASEB J. 2019 Jun;33(6):7387-7402.

Nakamura A, Morise J, Yabuno-Nakagawa K, Hashimoto Y, Takematsu H, Oka S.
Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1.
PLoS One. 2019 Jan 10;14(1):e0210193.

2018

Matsubara N, Imamura A, Yonemizu T, Akatsu C, Yang H, Ueki A, Watanabe N, Abdu-Allah H, Numoto N, Takematsu H, Kitazume S, Tedder TF, Marth JD, Ito N, Ando H, Ishida H, Kiso M, Tsubata T.
CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.
Front Immunol. 2018 Apr 19;9:820.

Tomioka M, Shimobayashi M, Kitabatake M, Ohno M, Kozutsumi Y, Oka S, Takematsu H.
Ribosomal protein uS7/Rps5 serine-223 in protein kinase-mediated phosphorylation and ribosomal small subunit maturation.
Sci Rep. 2018 Jan 19;8(1):1244.

Alborzian Deh Sheikh A, Akatsu C, Imamura A, Abdu-Allah HHM, Takematsu H, Ando H, Ishida H, Tsubata T.
Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.
Biochem Biophys Res Commun. 2018 Jan 1;495(1):854-859.

2017

Gao X, Deng L, Stack G, Yu H, Chen X, Naito-Matsui Y, Varki A, Galán JE.
Evolution of host adaptation in the Salmonella typhoid toxin.
Nat Microbiol. 2017 Dec;2(12):1592-1599.

Umekawa M, Ujihara M, Nakai D, Takematsu H, Wakayama M.
Ecm33 is a novel factor involved in efficient glucose uptake for nutrition-responsive TORC1 signaling in yeast.
FEBS Lett. 2017 Nov;591(22):3721-3729.

Takagi H, Nishibori Y, Katayama K, Katada T, Takahashi S, Kiuchi Z, Takahashi SI, Kamei H, Kawakami H, Akimoto Y, Kudo A, Asanuma K, Takematsu H, Yan K.
USP40 gene knockdown disrupts glomerular permeability in zebrafish.
Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F702-F715.

Naito-Matsui Y, Davies LR, Takematsu H, Chou HH, Tangvoranuntakul P, Carlin AF, Verhagen A, Heyser CJ, Yoo SW, Choudhury B, Paton JC, Paton AW, Varki NM, Schnaar RL, Varki A.
Physiological Exploration of the Long Term Evolutionary Selection against Expression of N-Glycolylneuraminic Acid in the Brain. Selected as one of "Editors' Picks".
J Biol Chem. 2017 Feb 17;292(7):2557-2570.

Siddiqui S, Schwarz F, Springer S, Khedri Z, Yu H, Deng L, Verhagen A, Naito-Matsui Y, Jiang W, Kim D, Zhou J, Ding B, Chen X, Varki N, Varki A.
Studies on the Detection, Expression, Glycosylation, Dimerization, and Ligand Binding Properties of Mouse Siglec-E.
J Biol Chem. 2017 Jan 20;292(3):1029-1037.

2016

Watanabe H, Okahara K, Naito-Matsui Y, Abe M, Go S, Inokuchi J, Okazaki T, Kobayashi T, Kozutsumi Y, Oka S, Takematsu H.
Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow.
Mol Biol Cell. 2016 Jul 1;27(13):2037-50.

Umekawa M, Ujihara M, Makishima K, Yamamoto S, Takematsu H, Wakayama M.
The signaling pathways underlying starvation-induced upregulation of α-mannosidase Ams1 in Saccharomyces cerevisiae.
Biochim Biophys Acta. 2016 Jun;1860(6):1192-201.

2015

Yabuno K, Morise J, Kizuka Y, Hashii N, Kawasaki N, Takahashi S, Miyata S, Izumikawa T, Kitagawa H, Takematsu H, Oka S.
A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets.
PLoS One. 2015 Dec 10;10(12):e0144560.

Takeuchi Y, Morise J, Morita I, Takematsu H, Oka S.
Role of Site-Specific N-Glycans Expressed on GluA2 in the Regulation of Cell Surface Expression of AMPA-Type Glutamate Receptors.
PLoS One. 2015 Aug 13;10(8):e0135644.

Itoh H, Matsuo H, Kitamura N, Yamamoto S, Higuchi T, Takematsu H, Kamikubo Y, Kondo T, Yamashita K, Sasada M, Takaori-Kondo A, Adachi S.
Enhancement of neutrophil autophagy by an IVIG preparation against multidrug-resistant bacteria as well as drug-sensitive strains.
J Leukoc Biol. 2015 Jul;98(1):107-17.

Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S.
Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.
Sci Rep. 2015 Jun 10;5:11163.

Major glycan structure underlying expression of the Lewis X epitope in the developing brain is O-mannose-linked glycans on phosphacan/RPTPβ.
Yaji S, Manya H, Nakagawa N, Takematsu H, Endo T, Kannagi R, Yoshihara T, Asano M, Oka S.
Glycobiology. 2015 Apr;25(4):376-85.

2014

Deng L, Song J, Gao X, Wang J, Yu H, Chen X, Varki N, Naito-Matsui Y, Galán JE, Varki A.
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell. 2014 Dec 4;159(6):1290-9.

Hutzler S, Ozgör L, Naito-Matsui Y, Kläsener K, Winkler TH, Reth M, Nitschke L.
The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells.
J Immunol. 2014 Jun 1;192(11):5406-14.

Yamane-Sando Y, Shimobayashi E, Shimobayashi M, Kozutsumi Y, Oka S, Takematsu H.
Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion.
Microbiologyopen. 2014 Apr;3(2):196-212.

Morise J, Kizuka Y, Yabuno K, Tonoyama Y, Hashii N, Kawasaki N, Manya H, Miyagoe-Suzuki Y, Takeda S, Endo T, Maeda N, Takematsu H, Oka S.
Structural and biochemical characterization of O-mannose-linked human natural killer-1 glycan expressed on phosphacan in developing mouse brains.
Glycobiology. 2014 Mar;24(3):314-24.

Naito-Matsui Y, Takada S, Kano Y, Iyoda T, Sugai M, Shimizu A, Inaba K, Nitschke L, Tsubata T, Oka S, Kozutsumi Y, Takematsu H.
Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cells.
J Biol Chem. 2014 Jan 17;289(3):1564-79.

2013

Nakagawa N, Takematsu H, Oka S.
HNK-1 sulfotransferase-dependent sulfation regulating laminin-binding glycans occurs in the post-phosphoryl moiety on α-dystroglycan.
Glycobiology. 2013 Sep;23(9):1066-74.

2012

Sun Y, Miao Y, Yamane Y, Zhang C, Shokat KM, Takematsu H, Kozutsumi Y, Drubin DG.
Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways.
Mol Biol Cell. 2012 Jun;23(12):2388-98.

Tochikura TS, Naito Y, Kozutsumi Y, Hohdatsu T.
Induction of feline immunodeficiency virus from a chronically infected feline T-lymphocyte cell line.
Res Vet Sci. 2012 Apr;92(2):327-32.

Adachi T, Harumiya S, Takematsu H, Kozutsumi Y, Wabl M, Fujimoto M, Tedder TF.
CD22 serves as a receptor for soluble IgM.
Eur J Immunol. 2012 Jan;42(1):241-7.

2011

Takematsu H, Yamamoto H, Naito-Matsui Y, Fujinawa R, Tanaka K, Okuno Y, Tanaka Y, Kyogashima M, Kannagi R, Kozutsumi Y.
Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway.
J Biol Chem. 2011 Aug 5;286(31):27214-24.

Yabuuchi H, Niijima S, Takematsu H, Ida T, Hirokawa T, Hara T, Ogawa T, Minowa Y, Tsujimoto G, Okuno Y.
Analysis of multiple compound-protein interactions reveals novel bioactive molecules.
Mol Syst Biol. 2011 Mar 1;7:472.

Abdu-Allah HH, Watanabe K, Completo GC, Sadagopan M, Hayashizaki K, Takaku C, Tamanaka T, Takematsu H, Kozutsumi Y, Paulson JC, Tsubata T, Ando H, Ishida H, Kiso M.
CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold.
Bioorg Med Chem. 2011 Mar 15;19(6):1966-71.

Yamamoto H, Naito Y, Okano M, Kanazawa T, Takematsu H, Kozutsumi Y.
Sphingosylphosphorylcholine and lysosulfatide have inverse regulatory functions in monocytic cell differentiation into macrophages.
Arch Biochem Biophys. 2011 Feb 1;506(1):83-91

2010年以前

Review

Morise J, Takematsu H, Oka S.
The role of human natural killer-1 (HNK-1) carbohydrate in neuronal plasticity and disease.
Biochim Biophys Acta Gen Subj. 2017 Oct;1861(10):2455-2461.

その他

Naito-Matsui Y, Takematsu H.
Remodeling of glycans using glycosyltransferase genes.
Methods Mol Biol. 2014;1200:379-87.