Contact information
Phone:+81-562-93-2440
e-mail:motosuzu*fujita-hu.ac.jp(In case of e-mail, please change * to @)
Address:1-98, Dengakugakubo, Kutsukake-cho, Toyoake-city, Aichi, 470-1192,
Japan
2023
Niimi A, Limsirichaikul1 S, Kano K, Mizutani Y, Takeuchi T, Sawangsri P, Tran DQ, Kawamoto Y, Suzuki M. LASP1, CERS6, and actin form ternary complex that promotes cancer cell migration. Cancers 2023, 15, 2781. doi: 10.3390/cancers15102781
Iwai M, Kajino T, Nakatochi M, Yanagisawa K, Hosono Y, Isomura H, Shimada Y, Suzuki M, Taguchi A. Long non-coding RNA TILR constitutively represses TP53 and apoptosis in lung cancer. Oncogene. 2023 Jan;42(5):364-373. doi: 10.1038/s41388-022-02546-w.
2022
Mizutani Y, Shiogama K, Inada KI, Takeuchi T, Niimi A, Suzuki M, Tsutsumi Y. Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during Formalin Fixation and Paraffin Embedding. Acta Histochem Cytochem. 2022 Oct 28;55(5):129-148. doi: 10.1267/ahc.22-00023.
Tamiya-Koizumi K, Otoki Y, Nakagawa K, Kannagi R, Mizutani N, Suzuki M, Kyogashima M, Iwaki S, Aoyama M, Murate T, Kitatani K, Kuga T, Mizutani Y, Tokumura A. Cellular concentrations of plasmalogen species containing a polyunsaturated fatty acid significantly increase under hypoxia in human colorectal cancer, Caco2 cells. Biochem Biophys Res Commun. 611: 1-7, 2022. doi: 10.1016/j.bbrc.2022.04.061.
Kondo Y, Watanabe S, Naoe A, Takeuchi T, Niimi A, Suzuki M, Asai N, Okada S, Yasui T, Inoue M, Suzuki T. Antitumor effect of polyphyllin D on liver metastases of Neuroblastoma. Ped Surg Int. 38: 1157-1163, 2022. doi: 10.1007/s00383-022-05146-7
Saruta M, Takahara K, Yoshizawa A, Niimi A, Takeuchi T, Nukaya T, Takenaka M, Zennami K, Fukaya K, Ichino M, Sasaki H, Kusaka M, Suzuki M, Sumitomo M, Shiroki R. Alanine-serine-cysteine-transporter 2 inhibition suppresses prostate cancer cell growth in vitro. J Clin Med. 11: 5466, 2022. doi: 10.3390/jcm11185466.
2021
Shi H, Niimi A, Takeuchi T, Shiogama K, Mizutani Y, Kajino T, Inada K, Hase T, Hatta T, Shibata H, Fukui T, Chen-Yoshikawa T-F, Nagano K, Murate T, Kawamoto Y, Tomida S, Takahashi T, Suzuki, M. CEBPgamma facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation. Cancer Sci, 2021 Jul;112(7):2770-2780. doi: 10.1111/cas.14928.
Khaledian B, Taguchi A, Shin-Ya K, Kondo-Ida L, Kagaya N, Suzuki M, Kajino T, Yamaguchi T, Shimada Y, Takahashi T. Inhibition of HSP90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma. Cancer Sci 112: 1225-1234, 2021. doi: 10.1111/cas.14786.
Isomura H, Taguchi A, Kajino T, Asai N, Nakatochi M, Kato S, Suzuki K, Yanagisawa K. Suzuki M. Fujishita T, Yamaguchi T. Takahashi M, Takahashi T. Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1alpha regulator. Cancer Sci 112: 1614-1623, 2021. doi: 10.1111/cas.14825.
Gondo N, Sakai Y, Zhang Z, Hato Y, Kuzushima K, Phimsen S, Kawashima Y, Kuroda M, Suzuki M, Okada S, Iwata H, Toyama T, Rezano A, and Kuwahara K. Increased chemosensitivity via BRCA2-independent DNA damage in DSS1- and PCID2-depleted breast carcinomas. Laboratory Investigation, 2021, 101(8):1048-1059. doi: 10.1038/s41374-021-00613-6.
Mizuno M, Khaledian B, Maeda M, Hayashi T, Mizuno S, Munetsuna E, Watanabe T, Kono S, Okada S, Suzuki M, Takao S, Minami H, Asai N, Sugiyama F, Takahashi S, Shimono Y. Adipsin-dependent secretion of hepatocyte growth factor regulates the adipocyte-cancer stem cell interaction. Cancers, 2021, 13(16), 4238. doi. 10.3390/cancers13164238
2020
Suzuki M, Cao K, Kato S, Mizutani N, Tanaka K, Arima, C, Tai MC, Nakatani N, Yanagisawa K, Takeuchi T, Shi H, Mizutani Y, Niimi A, Taniguchi T, Fukui T, Yokoi K, Wakahara K, Hasegawa, Y, Mizutani Y, Iwaki S, Fujii S, Satou A, Tamiya-Koizumi, K, Murate T, Kyogashima M, Tomida S, Takahashi T. CERS6 required for cell migration and metastasis in lung cancer. J Clin Mol Med, 24: 11949-11959, 2020. doi: 10.1111/jcmm.15817.
Takahashi Y, Tsutsumi Y, Takeuchi C, Shiogama K, Mizutani Y, Inada KI, Yamamichi N, Koike K. Nuclear staining of claudin-18 is a new immunohistochemical marker for diagnosing intramucosal well-differentiated gastric adenocarcinoma. Pathol Int. 2020 Sep;70(9):644-652. doi: 10.1111/pin.12978.
Sakai Y, Rezano A, Okada S, Ohtsuki T, Kawashima Y, Tsukamoto T, Suzuki M, Kohara M, Takeya M, Sakaguchi N, Kuwahara K. A Novel Cytological Model of B-Cell/Macrophage Biphenotypic Cell Hodgkin Lymphoma in Ganp-Transgenic Mice. Cancers (Basel) 12. pii: E204, 2020.
Yanagi H, Watanabe T, Nishimura T, Hayashi T, Kono S, Tsuchida H, Hirata M, Kijima Y, Takao S, Okada S, Suzuki M, Imaizumi K, Kawada K, Minami H, Gotoh N, Shimono Y. Upregulation of S100A10 in metastasized breast cancer stem cells. Cancer Sci 111: 4359-4370, 2020. doi: 10.1111/cas.14659.
Yoshizawa A, Takahara K, Saruta M, Zennami K, Nukaya T, Fukaya K, Ichino M, Fukami N, Niimi A, Sasaki H, Kusaka M, Suzuki M, Sumitomo M, Shiroki R, Combined alpha-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 inandrogen-receptor-variant-7-positive-prostate cancer cells. Prostate International 9: 18-24, 2021. Doi:10.1016/j.prnil.2020.07.001
Tsuji T, Yoshitomi H, Ishikawa Y, Koshizaki N, Suzuki M, Usukura J. A method to selectively internalise submicrometer boron carbide particles into cancer cells using surface transferrin conjugation for developing a new boron neutron capture therapy agent. J Exp Nanosci 15: 1-11, 2020
Inoue C, Sobue S, Kawamoto Y, Nishizawa Y, Ichihara M, Abe A, Hayakawa F, Suzuki M, Nozawa Y, Murate T. Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells. Biochem Biophys Res Commun. 525: 1074-1080, 2020. doi: 10.1016/j.bbrc.2020.02.165.
Inoue C, Sobue S, Mizutani N, Kawamoto Y, Nishizawa Y, Ichihara M, Takeuchi T, Hayakawa F, Suzuki M, Ito T, Nozawa Y, Murate T. Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes. Nagoya J Med Sci, 82: 261–280, 2020. doi:10.18999/nagjms.82.2.261
2019
Ishida R, Ueda K, Kitano T, Yamamoto T, Mizutani Y, Tsutsumi Y, Imoto K, Yamamori Y. Fatal community-acquired Bacillus cereus pneumonia in an immunocompetent adult man: a case report. BMC Infect Dis. 2019 Feb 27;19(1):197. doi: 10.1186/s12879-019-3836-3.
Kajino T, Shimamura T, Gong S, Yanagisawa K, Ida L, Nakatochi M, Griesing S, Shimada Y, Kano K, Suzuki M, Miyano S, Takahashi T. Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction. EMBO J 38: e98441, 2019. doi: 10.15252/embj.201798441.
Yamaguchi T, Hayashi M, Ida L, Yamamoto M, Lu C, Kajino T, Cheng J, Nakatochi M, Isomura H, Yamazaki M, Suzuki M, Fujimoto T, Takahashi T. ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma. Oncogene. 38: 5142-5157, 2019. doi: 10.1038/s41388-019-0785-7.
2018
Takahashi Y, Yamamichi N, Inada KI, Shiogama K, Sakurai K, Takeuchi C, Mizutani Y, Tsutsumi Y, Koike K. Nectin1 expression is frequently decreased in gastric cancers. Pathol Int. 2018 Oct;68(10):557-562. doi: 10.1111/pin.12721.
Inoue C, Sobue S, Aoyama Y, Mizutani N, Kawamoto Y, Nishizawa Y, Ichihara M, Abe A, Hayakawa F, Suzuki M, Nozawa Y, Murate T. BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells. Biochem Biophys Rep. 15: 69-75, 2018 doi: 10.1016/j.bbrep.2018.07.001