Case 214. 

Subacute necrotizing lymphadenitis (Kikuchi's disease) (23 y-o F)
       
  Biopsied cervical lymph node in a young Japanese complaining of fever and generalized malaise  
       

 

  Activated lymphoid cells are dispersed among macrophages phagocytizing apoptotic bodies (HE). Human herpes virus-6 genome is demonstrable in the lesion, but the etiological significance of HHV6 has been questioned.