Case 183. Molluscum contagiosum (45 y-o F)

　 　 　 　
　
Multiple dome-shaped perineal nodules (biopsy)
 　
　 　 　 　

　

 　 Note the change of stainability of the "molluscum body". In the granular layer, the inclusions are eosinophilic and granular, but in the cornified (parakeratotic) layer, they become homogeneous and increase basophilia (HE, high power).