Case 167. Lyme borreliosis (56 y-o M)

       
  Biopsy from erythema chronicum migrans on the abdomen around the site of tick bite, that happened in a highland of Nagano  
       

 

  Histologic features are nonspecific. Perivascular infiltration of small lymphocytes and some plasma cells is seen in the entire thickness of the dermis (HE). Warthin-Starry's silver was negative.