Case 153. 

E. coli-induced emphysematous pyelonephritis (64 y-o M)
       
  Autopsied kidneys of a patient of alcoholic cirrhosis, manifesting lethal septic shock (clinical course: 9 days)  
       

 

  Numerous Gram-negative rods are clustered within the necrotic renal tubules and around gas-filled bubbles (HE, high power). Microbial culture confirmed the infection of E. coli. This condition is called non-clostridial gas gangrene.