Case 149. Adenovirus infection of kidney (25 y-o M).

       
  Hemorrhagic necrotizing nephritis after bone marrow transplantation, manifesting macroscopic hematuria and cystitis.  
       

 

  High powered view shows intranuclear inclusions of full (smudgy) type or Cowdry's type A in the proximal tubular cells (HE). Renal involvement is often caused by adenovirus, type 11.