Case 133. Syphilis, primary (45 y-o M)

　 　 　 　
　
Biopsy from a painless penile ulcer
 　
　 　 　 　

　

 　 Highly coiled spiral microbes are identified among the squamous epithelium (Warthin-Starry's silver). This silver method is technically difficult, and the reproducibility is not satisfactory.