Case 199. Demodex folliculorum colonization (27 y-o M)
         
    Incidental biopsy findings of mite colonization in the hair follicle adjacent to the nevus of the facial skin    
         
   
Key words : Demodex folliculorum, Demodex brevis, acne demodecica
   
     
 
     
Two mites are seen in the infundibulum of the hair follicle. Four pairs of legs and basophilic granular material in the body are recognized (HE).   IgD is speficically deposited on the surface of the mite (immunostaining). IgG, IgA, IgM and IgE are negative. Deposition of α-1 antitrypsin and α-1 antichymotrypsin are also observed.
     
 
     
Reference case 199A
Demodex brevis among the sebaceous gland in the facial skin of a 34 y-o male (HE). A cut surface of a small mite with granulated cytoplasm. D. brevis parasitizes at the level of sebaceous gland lumen.
  Reference case 199A
Demodex brevis among the sebaceous gland in the facial skin of a 34 y-o male (PAS). The mite is rich in glycogen. The number of mites increases in case of acne demodecica. Steroid administration accelerates infestation.