Acute
necrotizing encephalopathy of childhood
(1 y-o M)
Consciousness disturbance killing the infant in three days
Key words : acute necrotizing encephalopathy, thalamic petechiae
The horozontal section of formalin-fixed swollen brain weighing 1,155 g reveals bilateral petechial hemorrhage in the thalamus.
In the thalamus, perivascular fresh hemorrhage and spongy edema are observed without inflammatory infiltration (HE). The features are consistent with acute encephalopathy accompanying symmetrical low densities in bilateral thalamus on CT scan (Mizuguchi).