Case 124. 
EBV-induced opportunistic brain lymphoma in AIDS (40 y-o M)
         
   
Biopsied multifocal brain tumors during the course of AIDS
   
         
   
Key words : EB virus, opportunistic lymphoma, AIDS
   
         
   
opportunistic infection
   
     
 
     
Diffuse large cell lymphoma is presented (HE). At autopsy, the lymphoma cells disseminted in systemic organs, including the gut.   The large-sized lymphoma cells strongly express CD20, a B-cell phenotype.
     
   
     
EBER-1, EBV-related small nuclear RNA, is expressed in the nucleus of most lymphoma cells (in situ hybridization).