Case 105. Toxoplasma meningitis (62 y-o M)
Incidental autopsy findings in case of progressive neuronal disorder
Key words : Toxoplasma gondii, purulent meningitis
opportunistic infection
Tachyzoites of Toxoplasma gondii are observed in the background of purulent meningitis (HE). Intracerebral lesions were mild in this case.   Oil immersion observation discloses that banana-shaped or crescentic tachyzoites (a proliferative form) possess a single nucleus (HE).
Indirect immunoperoxidase staining using a 1:500 diluted human serum with high Toxoplasma antibody titer demonstrates positive membrane signals on the disseminated tachyzoites.