Case 86. Mucormycosis of lung (60 y-o F)
         
    Autopsied lung with multifocal irregular hemorrhagic infarcts, seen after chemotherapy for acute leukemia    
         
   
Key words : mucormycosis, zygomycosis, hemorrhagic infarction
   
         
   
opportunistic infection
   
     
 
     
Mucormycosis (zygomycosis) is the infection by Zygomycetes, including Mucor ramosissimus, Rhizomucor pusillus and Rizopus oryzae. Common gross features include hemorrhagic infarction.   Weakly basophilic hyphae are seen among the mycotic thrombus formed in pulmonary arteries (HE).
     
 
     
Zygomycetes are microscopically featured by angioinvasiveness, weak reactivity with Grocott's silver, lack of septum formation and the width of the lamifying angle (Grocott).   Reference case 86A
Massive hemorrhagic necrosis of the stomach in systemic mucormycosis seen in a hemodialysis case (gross findings). Use of Deferoxamine (Desferal) in hemodialysis patients, as well as the state of severe diabetes mellitus, are known to increase the susceptibility to mucormycosis.