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Case 86. Mucormycosis of lung (60 y-o F)
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| Autopsied lung with multifocal irregular hemorrhagic infarcts, seen after chemotherapy for acute leukemia |
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Key words : mucormycosis, zygomycosis, hemorrhagic infarction
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opportunistic infection
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| Mucormycosis (zygomycosis) is the infection by Zygomycetes, including Mucor ramosissimus, Rhizomucor pusillus and Rizopus oryzae. Common gross features include hemorrhagic infarction. | Weakly basophilic hyphae are seen among the mycotic thrombus formed in pulmonary arteries (HE). | |
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| Zygomycetes are microscopically featured by angioinvasiveness, weak reactivity with Grocott's silver, lack of septum formation and the width of the lamifying angle (Grocott). | Reference case 86A Massive hemorrhagic necrosis of the stomach in systemic mucormycosis seen in a hemodialysis case (gross findings). Use of Deferoxamine (Desferal) in hemodialysis patients, as well as the state of severe diabetes mellitus, are known to increase the susceptibility to mucormycosis. |
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