Case 83. Rhinosporidiosis (42 y-o M)
Excised nasal polypoid lesion in a Kenyan adult
Key words : Rhinosporidium seeberi, nasal polyp
Sporangia of varying sizes are formed just beneath the squamous metaplastic epithelium. Mature sporangia contain numerous spores (HE). Inflammatory change is mild.   A large mature sporangium produces numerous spores, while a smaller immature sporangium contains amorphous basophilic cytoplasm (HE, high power).
The mature sporangium is Grocott-positive, while the immature sporangium is unreactive. Rhinosporidium seeberi is unculturable.