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Case 79. Histoplasmosis of lung (50 y-o M)
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| Surgical specimen of the apical encapsulated lung lesion in a resident along the Mississippi River |
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Key words : Histoplasma capsulatum, caseous necrosis
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| The histology is indistinguishable from tuberculosis or non-tuberculous mycobacteriosis. | Small-sized round yeasts are observed in the necrotic tissue. | |
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| Reference case 79A Systemic histoplasmosis in a child, with peripheral granulocytes infected with small yeast-form fungi (Giemsa). Capsule is not formed by Histoplasma capsulatum. The prognosis is poor. |
Reference case 79A Systemic histoplasmosis in a child, with bone marrow macrophages infected with small yeast form fungi (HE). Differential diagnosis includes leishmaniasis, cryptococcosis, and penicilliosis marneffei. |
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