Case 79. Histoplasmosis of lung (50 y-o M)
         
    Surgical specimen of the apical encapsulated lung lesion in a resident along the Mississippi River    
         
   
Key words : Histoplasma capsulatum, caseous necrosis
   
     
 
     
The histology is indistinguishable from tuberculosis or non-tuberculous mycobacteriosis.   Small-sized round yeasts are observed in the necrotic tissue.
     
 
     
Reference case 79A
Systemic histoplasmosis in a child, with peripheral granulocytes infected with small yeast-form fungi (Giemsa). Capsule is not formed by Histoplasma capsulatum. The prognosis is poor.
  Reference case 79A
Systemic histoplasmosis in a child, with bone marrow macrophages infected with small yeast form fungi (HE). Differential diagnosis includes leishmaniasis, cryptococcosis, and penicilliosis marneffei.