Case 42.  Yellow fever (28 y-o M)
         
   
An African adult showing fulminant liver failure
   
         
   
Key words :  yellow fever, Councilmann body
   
     
 
     
Edematous change is seen in the intermediate zone of the liver lobule, but no massive necrosis. Inflammatory infiltration is minimal (HE).   The hepatocytes in the intermediate zone reveal eosinophilic cytoplasmic coagulation, termed Councilman bodies (HE).