Case 40.  Hepatitis C virus infection (56 y-o F)
Liver biopsy from a patient with mild liver dysfunction
Key words :  hepatitis C virus, chronic hepatitis
Irregular portal fibrosis with piecemeal necrosis and mild lobular inflammation is seen, in association with fatty change of the hepatocytes and lymphoid follicle formation in the triad (HE).   Hepatitis C viral antigen is demonstrated in many hepatocytes in a granulated pattern (immunostaining).