Case 32. Chlamydia trachomatis infection of pharynx (20 y-o F)
Biopsy of swollen tonsil under clinical suspicion for malignant lymphoma
Key words : Chlamydia trachomatis, pharyngitis
Necrosis is a prominent finding in the biopsied tonsil (HE).   Lymphoid hyperplasia and exocytosis into the overlying squamous mucosa are observed (HE).
Cytoplasmic inclusion bodies filled with C. trachomatis antigen-positive granules are seen in some squamous cells (immunostaining).   Chlamydia trachomatis infection in Japan (1992)
The peak incidence is seen in the third decade, and females tend to be asymptomatic. Chlamydial urethritis in the male is often mediated through oral sex with an asymptomatic female carrier.