Case 19. Cryptosporidiosis (15 y-o M)
         
    Ileal biopsy from a healthy boy suffering from severe diarrhea, who stayed in a farm in Hokkaido for summer vacation with a close contact with cow    
         
   
Key words : Cryptosporidium parvum, acute enteritis, AIDS
   
         
   
zoonosis
   
     
 
     
A small number of tiny basophilic particles seen on the surface of the enterocytes (HE)   Tiny basophilic pathogens infected within the brush border of the enterocytes (HE, oil immersion)
     
 
     
Reference case 19A
Cysts of Cryptosporidium parvum in feces.
Acid-fast cysts in diarrheal stool in an African AIDS patient (Ziehl-Neelsen)
  Reference case 19B
Opportunistic cryptosporidiosis in a Japanese AIDS patient.
Autopsied jejunum with infection of Cryptosporidium parvum in the brush border of enterocytes (HE)
     
   
     
Reference case 19C
Opportunistic cryptosporidiosis in a Japanese AIDS patient.
Small pathogens in the brush border are identified by a 1:500 diluted serum of a healthy individual who suffered and recovered from acute, self-limiting cryptosporidiosis (indirect immunoperoxidase staining).