Case 15. VZV infection of GI tract (67 y-o M)
         
    Autopsied esophagus and duodenum from a kidney recepient taking corticosteroid and complaining of continuous diarrhea    
         
   
Key words : varicella-zoster virus, renal transplantation, steroid
   
         
   
opportunistic infection
   
     
 
     
Esophageal squamous mucosa with nuclear inclusions and multinucleated cells (HE, low power)   Esophageal squamous mucosa with nuclear inclusions and multinucleated cells (HE, high power)
     
 
     
VZV antigens (glycoprotein antigen expressing plasma membranes and nucleoprotein antigen located in the nucleus) in the esophageal squamous mucosa (immunostaining)   Duodenal mucosa with lamina proprial accumulation of foamy macrophages (no nuclear inclusions seen, HE)
     
   
     
VZV antigens expressing solely in the stromal component of the duodenal mucosa (immunostaining)