Case 14. Adenovirus infection of small bowel (10 y-o M)
         
    Autopsied colon from an ALL patient post bone marrow transplantation, suffering from severe hematochezia (1 L/day) lasting for 3 months    
         
   
Key words : adenovirus, enteritis, bone marrow transplantation, BK virus
   
         
   
opportunistic infection
   
     
 
     
Nuclear inclusion bodies (both Caudry type A and smudge type) seen in the nuclei of the epithelial cells of the gut (HE)   Electron micrograph of the viral inclusion, regularly consisting of hectangular particles, 70 nm in size
     
 
     
BK virus infection in the urinary bladder in the same patient
Nuclear inclusion bodies seen in the urinary bladder urothelial umbrella cells (HE). No hematuria recorded. Nuclear inclusion bodies are indistinguishable from those in the enteric lesion at the light microscopic level. Refer also to case 148.
  BK virus infection in the urinary bladder in the same patient
Electron micrograph of the viral inclusion, consisting of small sized particles, 40 nm in size. Ultrastructural study using routine paraffin sections is quite useful for the identification of the virus.