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Case 14. Adenovirus infection of small bowel (10 y-o M)
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| Autopsied colon from an ALL patient post bone marrow transplantation, suffering from severe hematochezia (1 L/day) lasting for 3 months | ||||
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Key words : adenovirus,
enteritis, bone marrow transplantation, BK virus
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opportunistic infection
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| Nuclear inclusion bodies (both Caudry type A and smudge type) seen in the nuclei of the epithelial cells of the gut (HE) | Electron micrograph of the viral inclusion, regularly consisting of hectangular particles, 70 nm in size | |
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| BK virus infection in the urinary bladder in the same patient Nuclear inclusion bodies seen in the urinary bladder urothelial umbrella cells (HE). No hematuria recorded. Nuclear inclusion bodies are indistinguishable from those in the enteric lesion at the light microscopic level. Refer also to case 148. |
BK virus infection in the urinary bladder in the same patient Electron micrograph of the viral inclusion, consisting of small sized particles, 40 nm in size. Ultrastructural study using routine paraffin sections is quite useful for the identification of the virus. |
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