2010-2022年

K. Hitachi, Y. Kiyofuji, M. Nakatani, K. Tsuchida.Myoparr-associated and -independent multiple roles of heterogeneous nuclear ribonucleoprotein K during skeletal muscle cell differentiation.Int.J. Mol. Sci.23(1):108 (2022)[Pubmed]

M. Ikemoto-Uezumi, H. Zhou, T. Kurosawa, Y. Yoshimoto, M. Toyoda, N. Kanazawa, T. Nakazawa, M. Morita, K. Tsuchida, A. Uezumi.Increased MFG-E8 at neuromuscular junctions is an exacerbating factor for sarcopenia-associated denervation.Aging Cell23(1):108 (2022)[Pubmed]

T. Kurosawa, K. Minato, M. Ikemoto-Uezumi, J. Hino, K. Tsuchida, A. Uezumi.Transgenic Expression of Bmp3b in Mesenchymal Progenitors Mitigates Age‐Related Muscle Mass Loss and Neuromuscular Junction Degeneration.Int.J. Mol. Sci.22, 10246(2021)[Pubmed]

S. Komatsu, J. Maruyama, T. Furuya, X. Yin, H. Yamaguchi, K. Hitachi, N. Miyashita, K. Tsuchida, M. Tani. J.Proteomic and Biological Analyses Reveal the Effect on Growth under Flooding Stress of Chickpea Irradiated with Millimeter Waves.Proteome Res.20(10), 4718-4727(2021)[Pubmed]

S. Komatsu, H. Yamaguchi, K. Hitachi, K. Tsuchida, Y. Kono, M. Nishimura.Proteomic and Biochemical Analyses of the Mechanism of Tolerance in Mutant Soybean Responding to Flooding Stress.Int.J. Mol. Sci.22(16),(2021)[Pubmed]

Q. Zhang, J. Lu, M. Jia, Y. Ma, M. Sun, X. Chen, X. Ma, Y. Yang, J. Kang, X. Zhang, S. Paiella, M. H.G Katz, K. Tsuchida, M. Schattner, S. Du.Evaluation of the reporting quality of clinical practice guidelines on pancreatic cancer using the RIGHT checklist.Annals of Translational Medicine9(13), 1088-1088(2021)[Pubmed]


T. Kusano, M. Nakatani, N. Ishiguro, K. Ohno, N. Yamamoto, M. Morita, H. Yamada, A. Uezumi, K. Tsuchida. Desloratadine Inhibits Heterotopic Ossification by Suppression of BMP2-Smad1/5/8 Signaling.J. Ortho. Res.39,1297-1304 (2021)[Pubmed]


K. Hitachi, M. Nakatani, Y. Kiyofuji, H. Inagaki, H. Kurahashi, K. Tsuchida.An Analysis of Differentially Expressed Coding and Long Non-Coding RNAs in Multiple Models of Skeletal Muscle Atrophy.Int. J. Mol. Sci. 2021 Mar 4;22(5):2558[Pubmed]

MA. Mohd Amnan, TL. Pua, SE. Lau, BC. Tan, H. Yamaguchi, K. Hitachi, K. Tsuchida, S. Komatsu.Osmotic stress in banana is relieved by exogenous nitric oxide.PeerJ. 2021 Feb 9;9:e10879.[Pubmed]


N. Uga, M. Nakatani, A. Yoshimura, K. Kumamoto, K. Tsuchida, S. Nagao, T. Tsuchiya, Y. Kondo, A. Naoe, S. Watanabe, T. Yasui, F. Hara, T. Suzuki. A new murine ileostomy model: recycling stool prevents intestinal atrophy in the distal side of the ileostomy.Fujita Medical J. 7(2),41-49 (2021)[Link]


A. Uezumi, M. Ikemoto-Uezumi, H. Zhou, T. Kurosawa, Y. Yoshimoto, M. Nakatani, K. Hitachi, H. Yamaguchi, S. Wakatsuki, T. Araki, M. Morita, H. Yamada, M. Toyoda, N. Kanazawa, T. Nakazawa, J. Hino, S-i. Fukada, K. Tsuchida. Mesenchymally-expressed Bmp3b maintains skeletal muscle integrity and decreased in age-related sarcopenia. J.Clin.Invest. 4;131(1):e139617. (2021)[Pubmed]


A. Hashiguchi, H. Yamaguchi, K. Hitachi, K. Watanabe.An Optimized Protein Extraction Method for Gel-Free Proteomic Analysis of Opuntia Ficus-Indica.Plants (Basel) . 2021 Jan 8;10(1):E115.[Pubmed]

A. Hashiguchi, K. Okabayashi, H. Yamaguchi, K. Tsuchida, K. Hitachi, H. Isoda. The effect of mung bean (Vigna radiata (L.)) coat extract on mouse liver metabolism during progesterone withdrawal. J. Medicinal Food 23(9), 967-977 (2020)[Pubmed]

G. Mustafa, M. Hasan, H. Yamaguchi, K. Hitachi, K. Tsuchida, S. Komatsu. A Comparative Proteomic Analysis of Engineered and Green Synthesized Silver Nanoparticles on Soybean Seedlings. J. Proteomics 224, 103833 (2020)[Pubmed]

Y. Yoshimoto, M. Uezumi, K. Hitachi, S.-I. Fukada, A. Uezumi. Methods for Accurate Assessment of Myofiber Maturity During Skeletal Muscle Regeneration. Front Cell Dev. Biol 8:267 (2020)[Pubmed]

K. Hitachi, M. Nakatani, S. Funasaki, I. Hijikata, M. Maekawa, M. Honda, K. Tsuchida. Expression levels of long non-coding RNAs are related to skeletal muscle mass in mice. International Journal of Molecular Sciences 21(5), 1628 (2020)[Pubmed]


K. Hitachi, K. Tsuchida. Regulatory roles of long non-coding RNAs in skeletal muscle differentiation, regeneration, and disorders. The Chemical Biology of Long Noncoding RNAs. RNA Technologies Series Vol.10 (Eds. Stefan Jurga and Jan Barciszewski) Springer Nature pp431-463 (2020)[Link]


Z. Zhong, T. Furuya, K. Ueno, H. Yamaguchi, K. Hitachi, K.Tsuchida, M. Tani, J. Tian, S. Komatsu. Proteomic Analysis of Irraduation with Millimeter Waves on Soybean Growth under Flooding Conditions. International Journal of Molecular Sciences 21, 486; doi:10.3390/ijms21020486 (2020)[Pubmed]


M. Saitoh, K. Takayama, K. Hitachi, A. Taguchi, A. Taniguchi, K. Tsuchida, Y. Hayashi. Discovery of a follistatin-derived myostatin inhibitory peptide. Bioorganic & Medicinal Chemistry Letters.30(3), 126892 (2020)[Pubmed]


K. Hitachi, H. Inagaki, H. Kurahashi, H. Okada, K. Tsuchida, M. Honda. Deficiency of Vgll2 Gene Alters the Gene Expression Profiling of Skeletal Muscle Subjected to Mechanical Overload. Frontiers in Sports and Active Living, Exercise Physiology, Data Report ARTICLE 09 October (2019)[Pubmed]


Z. Zhong, S. Liu, W, Zhu, Y. Ou, H. Yamaguchi, K. Hitachi, K. Tsuchida, J. Tian, S. Komatsu,. Phosphoproteomics reveals the biosynthesis of secondary metabolites in Catharanthus roseus under ultraviolet-B radiation. J. Proteomics Res. 18(9), 3328-3341 (2019)[Pubmed]


H. Ageta, K. Tsuchida. Invited review. Post-translational modification and protein sorting to small extracellular vesicles including exosomes by ubiquitin and UBLs. CMLS-Cellular and Molecular Life Sciences Jul 30. (2019)[Pubmed]

Z. Zhong, S. Liu,W. Zhu,Y. Ou, H. Yamaguchi, K. Hitachi, K. Tsuchida, J. Tian, S. Komatsu. Phosphoproteomics Reveals the Biosynthesis of Secondary Metabolites in Catharanthus roseus under Ultraviolet-B Radiation. J Proteome Res. (2019)[Pubmed]


K. Hitachi, K. Tsuchida. Data describing the effects of depletion of Myoparr, myogenin, Ddx17, and hnRNPK in differentiating C2C12 cells.Data in brief25,104172(2019)[Pubmed]

M. Ikemoto‐Uezumi, A. Uezumi, L. Zhang, H. Zhou, N. Hashimoto, K. Okamura, Y. Matsui, K. Tsukazaki, T. Hosoyama, M. Nakatani, M. Morita, H. Yamada, K. Tsuchida, SI. Fukada. Reduced expression of calcitonin receptor is closely associated with age related loss of the muscle stem cell pool. J. Cachexia, Sarcopenia and Muscle, rapid communication. Clinical Reports 2(1), e00081 (2019)[Pubmed]

K. Hitachi, M. Nakatani, K. Tsuchida. Long non-coding RNA Myoparr regulates GDF5 expression in denervated mouse skeletal muscle. Non-coding RNA 5(2), 33 (2019)[Pubmed]

M. Aslam, S.u. Rehman, A. Khatoon, M. Jamil,H. Yamaguchi, K. Hitachi, K. Tsuchida, X. Li, Y. Sunohara, H. Matsumoto, S. Komatsu. Molecular responses of maize shoot to plant derived smoke solution.Int J Mol Sci.20: 1319 (2019)[Pubmed]


T. Nagaoka, M. Furuse, T. Ohtsuka, K. Tsuchida, M. Kishi.Vangl2 interaction plays a role in the proteasomal degradation of Prickle2.Sicentific Reports. 9: 2912 (2019)[Pubmed]


HM. Jhanzab, A. Razzaq, Y. Bibi, F. Yasmeen, H. Yamaguchi, K. Hitachi, K. Tsuchida, S. Komatsu.Proteomic Analysis of the Effect of Inorganic and Organic Chemicals on Silver Nanoparticles in Wheat.Int J Mol Sci. 20(4)(2019)[Pubmed]


M. Honda, H. Tsuchimochi, K. Hitachi, S. Ohno.Transcriptional cofactor Vgll2 is required for functional adaptations of skeletal muscle induced by chronic overload.J Cell Physiol. (2019)[Pubmed]


K. Tsuchida. Evaluation of clinical outcomes of pancreatic cancer patients using circulating nucleic acids. Transl Gastroenterol Hepatol. 4;2. (2019)[Pubmed]


K. Hitachi, M. Nakatani, A. Takasaki, Y. Ouchi, A. Uezumi, H. Ageta, H. Inagaki, H. Kurahashi, K. Tsuchida. Myogenin promoter-associated lncRNA Myoparr is essential for myogenic differentiation.EMBO Rep.e47468.(2019)[Pubmed]


H. Ageta, N. Ageta-Ishihara, K. Hitachi, O. Karayel, T. Onouchi, H. Yamaguchi, T. Kahyo, K. Hatanaka, K. Ikegami, Y. Yoshioka, K. Nakamura, N. Kosaka, M. Nakatani, A. Uezumi, T. Ide, Y. Tsutsumi, H. Sugimura, M. Kinoshita, T. Ochiya, M. Mann, M. Setou, K. Tsuchida. UBL3 modification influences protein sorting to small extracellular vesicles.Nature communications. 9; 3936. (2018)[Pubmed]


K. Tsuchida, M. Nakatani, K. Hitachi. Therapeutic strategies against muscular dystrophy and related atrophic disorders. Journal of Translational Science. 5(5): 1-3, (2018)[Pubmed]


R. Kurokawa, R. Komiya, T. Oyoshi, Y. Matsuno, H. Tani, M. Katahira, K. Hitachi, Y. Iwashita, T. Yamashita, K. Kondo, R. Yoneda, Y. Yamaoki, N. Ueda, T. Mashima, N. Kobayashi, T. Nagata, A. Kiyoishi, M. Miyake, F. Kano, M. Murata, N. Hamad, K. Sasaki, N. Shoji. Multiplicity in Long Noncoding RNA in Living Cells. Biomedical Sciences. 4(2):18-23; (2018)[Pubmed]


X. Li, SU. Rehman, H. Yamaguchi, K. Hitachi, K. Tsuchida, T. Yamaguchi, Y. Sunohara, H. Matsumoto, S. Komatsu.Proteomic analysis of the effect of plant-derived smoke on soybean during recovery from flooding stress.J. Proteomics.181; 238-248. (2018)[Pubmed]


T. Kasai, M. Nakatani, N. Ishiguro, K. Ohno, N. Yamamoto, M. Morita, H. Yamada, K. Tsuchida, A. Uezumi. Promethazine hydrochloride inhibits ectopic fat cell formation in skeletal musce.

Am. J. Pathol. 187(12); 2627-2634. (2017)[Pubmed]


H. Sakai, S. Fukuda, M. Nakamura, A. Uezumi, Y-t. Noguchi, T. Sato, M. Morita, H. Yamada, K. Tsuchida, S. Tajbakhsh, S.-i. Fukada. Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity.PLoS One12(5); e0177516 (2017)[Pubmed]


C. Kimura, H. Ageta, H. Yamaguchi, T. Kuroiwa, D. Ikeda, M. Morita, K. Hayakawa, K. Tsuchida, H. Yamada. A comprehensive proteomics analysis of blood sera from patients of osteoarthritis. - Comparative study before and after total joint replacement surgery - J. Orthopedic Research Therapy 4 JORT-131 (2017)[Pubmed]


K. Hitachi, K. Tsuchida. Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle. Biomedical Advances, Musculoskeletal Disorder 9 (2017)[Link]


T. Kuroiwa, H. Ageta, D. Ikeda, M. Morita, K. Tsuchida, H. Yamada. Serum level of PRDX6 is elevated in osteoarthritis patients 3 months after surgery.Clinics in SurgeryVolume 2, 1378 (2017)[Pubmed]


A. Hashiguchi, K. Hitachi, W. Zhu, J. Tian, K. Tsuchida, S. Komatsu. Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: a proteomic study.J. Proteomics 161, 26-37 (2017) [Pubmed]


J. Hino, M. Nakatani, Y. Arai, K. Tsuchida, M. Shirai, M. Miyazato, K. Kangawa. Overexpression of bone morphogenetic protein-3b (BMP-3b) in adipose tissues protects against high-fat diet induced obesity with alteration of energy expenditure. Int. J. Obesity. 41(4), 483-488 (2017) [Pubmed]

K. Hitachi, K. Tsuchida. Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle. Oncotarget 8, 5943-5953 (2017)[Pubmed]

A Uezumi, M. Nakatani, M. Ikemoto-Uezumi, N. Yamamoto, M. Morita, H. Yamada, T. Kasai, Y. Miyagoe-Suzuki, S.-I. Takeda, S. Fukada, I. Nishino, and K. Tsuchida他. Cell surface protein profiling identifies distinctive markers of progenitor cells in human skeletal muscle. Stem Cell Report 7(2) : 263-278 (2016)[Pubmed]

A Uezumi, T. Kasai, K. Tsuchida. Identification, isolation, and characterization of mesenchymal progenitors in mouse and human skeletal muscle. Skeletal Muscle Regeneration, Springer Methods in Molecular Biology series. Methods Mol Biol1460:241-253. (2016)[Pubmed]

K. Tsuchida, K. Hitachi, M. Nakatani, A. Uezumi, H. Ageta. Chapter 1. The role of myostatin and related factors in muscle hypertrophy and atrophy in myostatin: Structure, role in muscle development and health implications. Nova Publishers, 2nd Quarter-2016.[Pubmed]

M. Yamaguchi, Y. Watanabe, A. Uezumi, M. Hoshino, K. Tsuchida, Y. Miyagoe-Suzuki, K. Tsujikawa, S.-I. Takeda, H. Yamamoto, S.I. Fukada 他. Calcitonin receptor signalling inhibits muscle stem cells from escaping the quiescent state and the niche. Cell Reports 13(2), 302-314. (2015)[Pubmed]

K. Tsuchida. Drug delivery systems for cancer treatment. Encyclopedia of Cancer 3rd ed. (Manfred Schwab Ed.) pp1-3 (2015)

Y. Ohsawa, K. Takayama, S. Nishimatsu, K. Tsuchida, Y. Sunada 他7人

The inhibitory core of the myostatin prodomain: Its interaction with both type I and II membrane receptors, and potential to treat muscle atrophy.PLoS One10(7), e0133713 (2015)[Pubmed]

M. Ikemoto-Uezumi, A. Uezumi, K. Tsuchida, S. Fukada, H. Yamamoto, N. Yamamoto, K. Shiomi, N. Hashimoto. Pro-IGF-II ameliorates age-related inefficient regenerative response by orchestrating self-reinforcement mechanism of muscle regeneration. Stem Cells33(8), 2456-2468 (2015)[Pubmed]


A. Uezumi, S. Fukada, N. Yamamoto, M. Ikemoto-Uezumi, M. Nakatani, M. Morita, A. Yamaguchi, H. Yamada, I. Nishino, Y. Hamada, K. Tsuchida. Identification and characterization of PDGFRα mesenchymal progenitors in human skeletal muscle.Cell Death Disease(Nature Publishing Group) 5, e1186 (2014)[Pubmed]


K. Tsuchida. Myokines and signal crosstalk between skeletal muscle and adipose tissue. Austin J Endo Metab 1(3), 2 (2014)[Pubmed]


A. Uezumi, M. Ikemoto-Uezumi, K. Tsuchida. Role for nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle. Frontiers in Physiology:Frontiers in Skeletal Muscle Wasting, Regeneration and Stem Cells. 5, 68, 1-11 (2014)[Pubmed]

K. Hitachi, K. Tsuchida. Role of microRNAs in muscle hypertrophy. Role of microRNAs in muscle hypertrophy. Frontiers in Physiology :MicroRNA and Skeletal Muscle Function: Novel Potential Roles in Exercise, Diseases, and Aging. 4, 408, 1-7 (2014)[Pubmed]

K. Hitachi, M. Nakatani, K. Tsuchida. Myostatin signaling regulates Akt activity via the regulation of miR-486 expression.Int. J. Biochem. Cell Biol.47:93-103(2014)[Pubmed]


D. Ikeda, H. Ageta, K. Tsuchida, H. Yamada. iTRAQ-based proteomics reveals novel biomarkers of osteoarthritis.BioMarkers18(7):565-572 (2013)[Pubmed]

K. Tsuchida, T. Oishi, A. Uezumi, H. Yamada. Origin and therapeutic strategies for ectopic bone formation in skeletal muscle.Human Genet Embryol3:2 (2013)

T. Oishi, A. Uezumi, A. Kanaji, N. Yamamoto, A. Yamaguchi, H. Yamada, K. Tsuchida. Osteogenic differentiation capacity of human skeletal muscle-derived progenitor cells.PLoS One8(2), e56641 (2013)[Pubmed]

T. Murakami, M. Nakatani, M. Kokubo, H. Nakatsuji, M. Inada, H. Imahori, M. Yudasaka, S. Iijima, K. Tsuchida, Mechanism of cell interactions with water-dispersed carbon nanohorns.Nanoscience and Nanotechnology Letters5(3), 402-407 (2013)

T. Murakami, M. Yudasaka, S. Iijima, K. Tsuchida. Characterization of inorganic nanomaterials as therapeutic vehicles.Recent Advances Medicinal Chemistry1, 165-188 (2012)

Y. Ohsawa, T. Okada, S. Nishimatsu, M. Ishizaki, T. Suga, M. Fujino, T. Murakami, M. Uchino, K. Tsuchida, S. Noji, A. Hinohara, T. Shimizu, K. Shimizu, Y. Sunada. An inhibitor of transforming growth factor beta type I receptor ameliorates muscle atrophy in a mouse model of caveolin 3-deficient muscular dystrophy.Lab. Invest.92(8), 1100-1114 (2012)[Pubmed]

M. Nakatani, M. Kokubo, Y. Ohsawa, Y. Sunada, K. Tsuchida. Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis.Am. J. Physiol. Endocrinol. Metab.300(3), E543-553 (2011)[Pubmed](Editor’s Choice selected)

H. Ageta, K. Tsuchida. Multifunctional roles of activins in the brain.Vitamins and Hormones(G. Litwack Ed.) 85, 185-206 (2011)[Pubmed]

M. Nakamura, Y. Tahara, Y. Ikehara, T. Murakami, K. Tsuchida, S. Iijima, I. Waga, M. Yudasaka. Single-walled carbon nanohorns as drug carriers: adsorption of prednisolone and anti-inflammatory effects on arthritis.Nanotechnology22(46), 465102 (2011)[Pubmed]

A. Uezumi, T. Ito, S. Takeda, K. Tsujikawa, K. Tsuchida, H. Yamamoto, S. Fukada 他11名

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle.J. CellScience124(Pt21), 3654-3664 (2011)[Pubmed]

M. Ishikawa, N. Nishijima, J. Shiota, H. Sakagami, K. Tsuchida, M. Mizukoshi, M. Fukuchi, M. Tsuda, A. Tabuchi. Involvement of the SRF coactivator megakaryoblastic leukemia in the activin-regulated dendritic complexity of rat cortical neurons.J. Biol. Chem.285(43), 32734-32743 (2010)[Pubmed]

S.-J. Lee, Y.-S. Lee, T.A. Zimmers, A. Soleimani,M.M. Matzuk, K. Tsuchida, R. D. Cohn, E. R. Barton. Regulation of muscle mass by follistatin and activins.Mol. Endocrinol.24(10), 1998-2008 (2010)[Pubmed]

T. Murakami, W. Wijagkanalan, M. Hashida, K. Tsuchida. Intracellular drug delivery by genetically engineered high density lipoprotein nanoparticle.Nanomed. 5(6), 867-879 (2010)[Pubmed]

T. Murakami, K. Tsuchida, M. Hashida, H. Imahori. Size control of lipid-based drug carrier by drug loading.Mol. BioSystems6, 789-791 (2010)[Pubmed](Highlights in Chemical Biology)

H. Ageta, S. Ikegami, M. Miura, M. Masuda, R. Migishima, T. Hino, N. Takashima, A. Murayama, H. Sugino, M. Setou, S. Kida, M. Yokoyama, Y. Hasegawa, K. Tsuchida, T. Aosaki, K. Inokuchi. Activin plays a key role in the maintenance of long-term memory and late-LTP.Learning and Memory17(4), 176-185 (2010)[Pubmed](press released) (Editor’s choice selected)

A. Uezumi, S. Fukada, N. Yamamoto, S.-I. Takeda, K. Tsuchida. Mesenchymal progenitors distinct from muscle satellite cells contribute to ectopic fat cell formation in skeletal muscle.Nature Cell Biology12(2), 143-152 (2010)[Pubmed](News & Views selected)

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